Hai everybody.
How's your day?
I do miss about us. Somehow, past is past.
Friends Forever :)
Today i would like to share about Antihistamines and my short note....
What is Histamines?
Its a natural reaction's body produces chemical in immune system which is protect body from foreign object ( against illness and infection). So, antihistamines work by blocking the receptor thats effected to reduces inflamation.
Antihistamines work to relief runny nose,allergic ( etc: skin, conjunctivitis,food allergies,rhinitis)
Antihistamines drug are classified in three group:
1) 1st generation : Chlorphenamine & Diphenhydramine
2) 2nd and 3rd generation :Loratadine, Cetirizine
3) H2 receptor antagonist : used to treat stomach ulcers
Side effect
1) 1st generation : Drowsiness, impaired thinking, dry mouth, dizziness, constipation, blurred vission.
2) 2nd and 3rd generation :headache, dry mouth,dry nose
3) H2 receptor antagonist : diarrhoea, headahe,dizziness
Common antihistamines dosing practice in hospital :
Montelukast
> 6 months until 6 years old : 4 mg ON ( 1 Sachet)
6 years until 15 years : 5mg ON (1 Tablet)
Cetirizine
1 years until 2 years : 2.5mg BD
2 years until 6 years : 5mg OD
6 years until Adults : 10mg OD
Loratadine
2 years until 6 years : 5mg OD
6 years until Adult : 10mg OD
Chlorphenamine
2 years to 6 years : 1mg TDS (max 6mg/day)
: 0.1mg/kg TDS (syrup)
6 years untul Adult : 2mg TDS (max 12mg/day)
Promethazine
2 years to 5 years : 5mg BD
Antihistamine/ antiemetic: 0.2mg/kg TDS (syrup)
Sedative : 0.5mg/kg TDS (syrup)
5years until 10 years : 5mg to 10mg BD
> 10 years : 10mg to 20mg BD/TDS
Diphenhydramine (syrup)
2 years until 12 years : 1mg/kg TDS (usually 5ml TDS)
> 13 years until Adult : 10ml - 15ml TDS
Hopefully, may useful and SAY NO TO MERS!
Till then.
May you all had a great weekend. :) *Big Smile*
p/s :
1) Caution : Kids under 2 years old is contraindicate (CANNOT GIVE) anthistamines!
2) Sesaat di ke Abadi-an :)
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